Primate Gene Therapy

Diverse NHP species including Cynomolgus monkeys, Rhesus monkeys, African Green Monkeys, & Marmosets. Our Large colonies allow for rapid screening to obtain anti-AAV seronegative study candidates.

Large domestic breeding colonies allowing for NHP studies at any age range

Genetic, small molecule and protein-based biomarkers.

Screening capability for array of anti-AAV antibodies and neutralizing antibodies serotypes including AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAVrh10, AAVhu68.

Barrier housing allowing for maintaining pre-screened AAV negative primates to support programs through completion with no study delays due to high seropositive rates or unexpected seroconversion.

Expert in multiple gene therapy delivery routes including:

Intrahepatic

Intrathecal

Intraocular

Intravenous

Intratracheal

Intrahepatic

Intrathecal

Intraocular

Intravenous

Intratracheal

Intramuscular

Intramuscular

Intranasal

Intraperitoneal

Intracerebroventricular

Intravitreal

Intranasal

Intraperitoneal

Intracerebroventricular

Intravitreal

Expert in repeated biopsies, surgical tissue excisions, and CSF sampling.

Partial or full sterile tissue collection with gene and protein expression quantification or samples shipped to sponsor.

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